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Mouse Twist1 activation kit by CRISPRa

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SKU
GA204498
Twist1 CRISPRa kit - CRISPR gene activation of mouse twist basic helix-loop-helix transcription factor 1
  $1,657.00
4 Weeks*

Other products for "Twist1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Twist1
Locus ID 22160
Components

GA204498G1, Twist1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204498G2, Twist1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204498G3, Twist1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_011658
UniProt ID P26687
Synonyms bHLHa38; M-Twist; Pde; pdt; Ska10; Ska; Twist
Summary Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. This gene encodes a bHLH transcription factor that is evolutionarily conserved from invertebrates to humans, and was originally identified in Drosophila as an essential gene involved in early mesoderm development and dorsal-ventral patterning in the embryo. This protein plays a role in cancer by regulating the epithelial-mesenchymal transition (EMT), a process that is critical for metastasis initiation, and promoting tumor progression. Mutations in the human gene are associated with Saethre-Chotzen syndrome (SCS). Mice with heterozygous mutations in this gene exhibit cranofacial and structural defects similar to those seen in human SCS patients. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN318498 Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318498BN Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318498LP Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318498RB Twist1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN518498 Twist1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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