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Mouse Tph1 activation kit by CRISPRa

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SKU
GA204422
Tph1 CRISPRa kit - CRISPR gene activation of mouse tryptophan hydroxylase 1
  $1,657.00
4 Weeks*

Other products for "Tph1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tph1
Locus ID 21990
Components

GA204422G1, Tph1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204422G2, Tph1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204422G3, Tph1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001136084, NM_001276372, NM_009414
UniProt ID P17532
Synonyms Tph
Summary This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase family. The encoded protein is one of two tryptophan hydroxylase enzymes that catalyze the first and rate limiting step in the biosynthesis of the hormone and neurotransmitter, serotonin. This gene is expressed in peripheral organs, while tryptophan hydroxylase 2 is expressed in neurons. The encoded protein is involved in the development of hypoxia-induced elevations in pulmonary pressures and pulmonary vascular remodeling, and has also been implicated as a regulator of immune tolerance. Disruption of this gene is associated with cardiac dysfunction. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN518087 Tph1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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