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Mouse Cd40lg activation kit by CRISPRa

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SKU
GA204401
Cd40lg CRISPRa kit - CRISPR gene activation of mouse CD40 ligand
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

TA386234 Recombinant Anti-CD40L (Clone MR1)
200 ug
$770.00

Other products for "Cd40lg"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Cd40lg
Locus ID 21947
Components

GA204401G1, Cd40lg gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204401G2, Cd40lg gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204401G3, Cd40lg gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_011616
UniProt ID P27548
Synonyms CD40-L; Cd40l; CD154; gp39; HIGM1; IGM; IMD3; Ly-62; Ly62; T-BAM; Tnfsf5; Tnlg8b; TRAP
Summary Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (PubMed:1374165).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN502919 Cd40lg - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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