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Mouse Tgfb2 activation kit by CRISPRa

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SKU
GA204320
Tgfb2 CRISPRa kit - CRISPR gene activation of mouse transforming growth factor, beta 2
  $1,657.00
4 Weeks*

Other products for "Tgfb2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tgfb2
Locus ID 21808
Components

GA204320G1, Tgfb2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204320G2, Tgfb2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204320G3, Tgfb2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_009367
UniProt ID P27090
Synonyms BB105277; Tgf-beta2; Tgfb-2
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Mice lacking a functional copy of this gene display developmental defects in multiple organs and perinatal lethality. Heterozygous mutant mice exhibit aortic root aneurysm. This gene encodes multiple isoforms that may undergo similar proteolytic processing. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN317484 Tgfb2 - mouse gene knockout kit via CRISPR 1 kit
$1,657.00
KN517484 Tgfb2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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