Mouse Tap1 activation kit by CRISPRa

SKU
GA204208
Tap1 CRISPRa kit - CRISPR gene activation of mouse transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Tap1
Locus ID 21354
Components

GA204208G1, Tap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204208G2, Tap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204208G3, Tap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001161730, NM_013683
UniProt ID P21958
Synonyms ABC17; Abcb2; APT1; Ham-1; Ham1; MTP1; PSF1; RING4; TAP; Tap-1; Y3
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This protein forms a heterodimer with Tap2 that transports short peptides from the cytosol into the endoplasmic reticulum lumen. Mutations in the human gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2009
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Other Versions
SKU Description Size Price
KN517175 Tap1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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