Mouse Stk11 activation kit by CRISPRa

SKU
GA204139
Stk11 CRISPRa kit - CRISPR gene activation of mouse serine/threonine kinase 11
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Stk11
Locus ID 20869
Components

GA204139G1, Stk11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204139G2, Stk11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204139G3, Stk11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001301853, NM_001301854, NM_011492, NR_126043
UniProt ID Q9WTK7
Synonyms AA408040; Lkb1; Par-4; R75140
Summary This gene encodes a member of the serine/threonine kinase family. The encoded protein, a known tumor suppressor, activates (via phosphorylation) adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. This upstream regulation of the AMPK pathway is thought to regulate a number of different processes, including cell metabolism, cell polarity, apoptosis and DNA damage response. Mutations in a similar gene in human have been associated with Peutz-Jeghers syndrome. Alternative splicing results in multiple transcript variants, including the S isoform which plays a potential role in spermiogenesis. provided by RefSeq, Sep 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN516868 Stk11 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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