Mouse Sptlc2 activation kit by CRISPRa

SKU
GA204099
Sptlc2 CRISPRa kit - CRISPR gene activation of mouse serine palmitoyltransferase, long chain base subunit 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sptlc2
Locus ID 20773
Components

GA204099G1, Sptlc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204099G2, Sptlc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204099G3, Sptlc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_011479
UniProt ID P97363
Synonyms LCB2; LCB2a; Spt2
Summary This gene encodes a long chain base subunit of serine palmitoyltransferase. The enzyme, serine palmitoyltransferase, consists of two different subunits, and is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. A mutant allele of this gene in mice is used as a model for the human disease 'Susceptibilty to Psoriasis 1'. Mutations in the human gene are associated with hereditary sensory neuropathy type I. provided by RefSeq, Sep 2015
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Other Versions
SKU Description Size Price
KN516687 Sptlc2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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