Mouse Serpina3g activation kit by CRISPRa

SKU
GA204061
Serpina3g CRISPRa kit - CRISPR gene activation of mouse serine (or cysteine) peptidase inhibitor, clade A, member 3G
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Serpina3g
Locus ID 20715
Components

GA204061G1, Serpina3g gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204061G2, Serpina3g gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204061G3, Serpina3g gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_009251, NM_001353612, NM_001353613
UniProt ID Q5I2A0
Synonyms 2A2; AI119734; spi2; Spi2-1; Spi2/eb.1; Spi2A
Summary Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN515566 Serpina3g - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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