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Mouse Siglec1 activation kit by CRISPRa

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SKU
GA203997
Siglec1 CRISPRa kit - CRISPR gene activation of mouse sialic acid binding Ig-like lectin 1, sialoadhesin
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

TA385758 Recombinant Anti-CD169 (Clone 3D6.112 (recombinant version))
100 ug
$995.00

Other products for "Siglec1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Siglec1
Locus ID 20612
Components

GA203997G1, Siglec1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203997G2, Siglec1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203997G3, Siglec1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_011426
UniProt ID Q62230
Synonyms Cd169; Siglec-1; Sn
Summary Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN515777 Siglec1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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