Mouse Smpd2 activation kit by CRISPRa

SKU GA203987

Smpd2 CRISPRa kit - CRISPR gene activation of mouse sphingomyelin phosphodiesterase 2, neutral

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Smpd2
• Locus ID: 20598
• Components:

  GA203987G1, Smpd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA203987G2, Smpd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA203987G3, Smpd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_009213
• UniProt ID: O70572
• Synonyms: AW108287; nSMase; nSMase1
• Summary: This gene encodes a protein with similarity to the human nSMase1 protein. In humans, the nSMase1 protein was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009]