Mouse Ccl5 activation kit by CRISPRa

SKU
GA203806
Ccl5 CRISPRa kit - CRISPR gene activation of mouse chemokine (C-C motif) ligand 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ccl5
Locus ID 20304
Components

GA203806G1, Ccl5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203806G2, Ccl5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203806G3, Ccl5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_013653
UniProt ID P30882
Synonyms MuRantes; RANTES; Scya5; SISd; TCP228
Summary Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN502795 Ccl5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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