Mouse Scn9a activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | Scn9a |
| Locus ID | 20274 |
| Components |
GA203786G1, Scn9a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203786G2, Scn9a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203786G3, Scn9a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001290674, NM_001290675, NM_018852 |
| UniProt ID | Q62205 |
| Synonyms | mKIAA4197; Nav1.7; PN1 |
| Summary | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:15123669). It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:15314237).UniProtKB/Swiss-Prot Function |
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