Mouse Polr1b activation kit by CRISPRa

SKU
GA203699
Polr1b CRISPRa kit - CRISPR gene activation of mouse polymerase (RNA) I polypeptide B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Polr1b
Locus ID 20017
Components

GA203699G1, Polr1b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203699G2, Polr1b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203699G3, Polr1b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_009086
UniProt ID P70700
Synonyms 128kDa; D630020H17Rik; RPA2; RPA116; RPA135; Rpo1-2
Summary DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN513593 Polr1b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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