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Mouse Rab17 activation kit by CRISPRa

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SKU
GA203525
Rab17 CRISPRa kit - CRISPR gene activation of mouse RAB17, member RAS oncogene family
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

TA303329 Goat Polyclonal Antibody against Rab17
100 ug
$565.00

Other products for "Rab17"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Rab17
Locus ID 19329
Components

GA203525G1, Rab17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203525G2, Rab17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203525G3, Rab17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001159725, NM_008998
UniProt ID P35292
Synonyms AW413472
Summary The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development. May also play a role in cell migration.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN514335 Rab17 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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