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Mouse Ptgds activation kit by CRISPRa

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SKU
GA203450
Ptgds CRISPRa kit - CRISPR gene activation of mouse prostaglandin D2 synthase (brain)
  $1,657.00
4 Weeks*

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100 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ptgds
Locus ID 19215
Components

GA203450G1, Ptgds gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203450G2, Ptgds gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203450G3, Ptgds gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_008963
UniProt ID O09114
Synonyms 21kDa; L-PGDS; PGD2; PGDS; PGDS2; Ptgs3
Summary Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN514167 Ptgds - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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