Mouse Pomc activation kit by CRISPRa

SKU
GA203321
Pomc CRISPRa kit - CRISPR gene activation of mouse pro-opiomelanocortin-alpha
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pomc
Locus ID 18976
Components

GA203321G1, Pomc gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203321G2, Pomc gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203321G3, Pomc gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001278581, NM_001278582, NM_001278583, NM_001278584, NM_008895
UniProt ID P01193
Synonyms ACTH; alpha-MSH; alphaMSH; BE; Beta-LPH; beta-MSH; Clip; Gamma-LPH; gamma-MSH; Npp; Pomc-1; Pomc1
Summary This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN513624 Pomc - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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