Mouse Pfkl activation kit by CRISPRa

SKU
GA203188
Pfkl CRISPRa kit - CRISPR gene activation of mouse phosphofructokinase, liver, B-type
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pfkl
Locus ID 18641
Components

GA203188G1, Pfkl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203188G2, Pfkl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203188G3, Pfkl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_008826, NM_001358793
UniProt ID P12382
Synonyms AA407869; ATP-PFK; PFK-L
Summary Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (By similarity). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by controlling cellular NADPH biosynthesis and NADPH oxidase-derived reactive oxygen species. Upon macrophage activation, drives the metabolic switch toward glycolysis, thus preventing glucose turnover that produces NADPH via pentose phosphate pathway (PubMed:26194095).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN513143 Pfkl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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