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Mouse Pax6 activation kit by CRISPRa

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SKU
GA203104
Pax6 CRISPRa kit - CRISPR gene activation of mouse paired box 6
  $1,657.00
4 Weeks*

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100 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Pax6
Locus ID 18508
Components

GA203104G1, Pax6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203104G2, Pax6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203104G3, Pax6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001244198, NM_001244200, NM_001244201, NM_001244202, NM_013627
UniProt ID P63015
Synonyms 1500038E17Rik; AEY11; Dey; Gsfaey11; Pax-6; Sey
Summary This gene encodes a homeobox-containing protein that functions as a regulator of transcription. It plays a key role in the development of neural tissues, particularly the eye. Activity of this protein is also required for expression of glucagon in the pancreas. This gene is regulated by multiple enhancers located up to tens or hundreds of kilobases upstream and downstream of the transcription start sites. Mutations in this gene or deletion of these regulatory elements results in severe defects in eye development. Alternative splicing and the use of alternative promoters results in multiple transcript variants, some of which encode proteins that lack the N-terminal paired domain. provided by RefSeq, Jul 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN512848 Pax6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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