Mouse P2rx7 activation kit by CRISPRa

SKU
GA203078
P2rx7 CRISPRa kit - CRISPR gene activation of mouse purinergic receptor P2X, ligand-gated ion channel, 7
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol P2rx7
Locus ID 18439
Components

GA203078G1, P2rx7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203078G2, P2rx7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203078G3, P2rx7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001038839, NM_001038845, NM_001038887, NM_001284402, NM_011027
UniProt ID Q9Z1M0
Synonyms AI467586; P2X(7); P2X7R
Summary Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN512714 P2rx7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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