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Mouse Sigmar1 activation kit by CRISPRa

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SKU
GA203053
Sigmar1 CRISPRa kit - CRISPR gene activation of mouse sigma non-opioid intracellular receptor 1
  $1,657.00
4 Weeks*

Other products for "Sigmar1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sigmar1
Locus ID 18391
Components

GA203053G1, Sigmar1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203053G2, Sigmar1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203053G3, Sigmar1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001286538, NM_001286539, NM_001286540, NM_001286541, NM_001286542, NM_001286551, NM_001286605, NM_011014
UniProt ID O55242
Synonyms Oprs1; Sig1R; sigma1R
Summary This gene encodes a transmembrane protein located in the endoplasmic reticulum. The encoded protein is a receptor that binds several endogenous ligands, including N,N-dimethyltryptamine, progesterone and pregnenolone and a variety of of non-opiate compounds. The encoded protein plays a role in regulating the activity of ion channels, acting as a chaperone and protecting cells from oxidative stress. In humans, this receptor has been associated with Alzheimer's and Parkinson's diseases, stroke and numerous disease conditions such as depression, pain and addiction. Alternative splicing results in multiple transcript variants encoding different isoforms.provided by RefSeq, Nov 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN515783 Sigmar1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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