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Mouse Oprk1 activation kit by CRISPRa

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SKU
GA203050
Oprk1 CRISPRa kit - CRISPR gene activation of mouse opioid receptor, kappa 1
  $1,657.00
4 Weeks*

Other products for "Oprk1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Oprk1
Locus ID 18387
Components

GA203050G1, Oprk1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203050G2, Oprk1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203050G3, Oprk1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001204371, NM_011011
UniProt ID P33534
Synonyms K-OR-1; KOR; KOR-1; MSL-1; Oprk2; R21
Summary This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. provided by RefSeq, Dec 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN512615 Oprk1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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