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Mouse Ogdh activation kit by CRISPRa

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SKU
GA203010
Ogdh CRISPRa kit - CRISPR gene activation of mouse oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  $1,657.00
4 Weeks*

Other products for "Ogdh"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ogdh
Locus ID 18293
Components

GA203010G1, Ogdh gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203010G2, Ogdh gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203010G3, Ogdh gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001252282, NM_001252283, NM_001252287, NM_001252288, NM_010956, NM_001361902, NM_001361903, NM_001361904, NM_001361905
UniProt ID Q60597
Synonyms 2210403E04Rik; 2210412K19Rik; AA409584; d1401; mKIAA4192
Summary 2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN511447 Ogdh - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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