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Mouse Ntan1 activation kit by CRISPRa

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SKU
GA202981
Ntan1 CRISPRa kit - CRISPR gene activation of mouse N-terminal Asn amidase
  $1,657.00
4 Weeks*

Other products for "Ntan1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ntan1
Locus ID 18203
Components

GA202981G1, Ntan1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202981G2, Ntan1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202981G3, Ntan1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_010946, NR_144374
UniProt ID Q64311
Synonyms PNAA; PNAD
Summary The protein encoded by this gene functions in a step-wise protein degradation process through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asparagine residues on proteins to produce N-terminal L-Aspartate. L-Aspartate substrates are subsequently conjugated to L-Arginine, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Mice with a knock-out of this gene are viable, fertile, and outwardly normal, but show impairments in spontaneous activity and spatial memory, relative to their wild-type counterparts. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN511282 Ntan1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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