Mouse Ctnnd2 activation kit by CRISPRa

SKU
GA202954
Ctnnd2 CRISPRa kit - CRISPR gene activation of mouse catenin (cadherin associated protein), delta 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ctnnd2
Locus ID 18163
Components

GA202954G1, Ctnnd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202954G2, Ctnnd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202954G3, Ctnnd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_008729, NM_001355502
UniProt ID O35927
Synonyms Catnd2; neurojugin; Nprap
Summary Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:17993462) (PubMed:25807484). Involved in the regulation of canonical Wnt signaling (By similarity). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (PubMed:20623542). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules. Functions as a transcriptional activator when bound to ZBTB33 (PubMed:15282317).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN503971 Ctnnd2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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