Mouse Notch3 activation kit by CRISPRa

SKU
GA202938
Notch3 CRISPRa kit - CRISPR gene activation of mouse notch 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Notch3
Locus ID 18131
Components

GA202938G1, Notch3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202938G2, Notch3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202938G3, Notch3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_008716
UniProt ID Q61982
Synonyms AW229011; hpbk; N3
Summary Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). May play a role during CNS development.UniProtKB/Swiss-Prot Function
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Other Versions
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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