Mouse Nkx2-5 activation kit by CRISPRa

SKU
GA202910
Nkx2-5 CRISPRa kit - CRISPR gene activation of mouse NK2 homeobox 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nkx2-5
Locus ID 18091
Components

GA202910G1, Nkx2-5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202910G2, Nkx2-5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202910G3, Nkx2-5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_008700
UniProt ID P42582
Synonyms Csx; Nkx-2.5; Nkx2.5; tinman
Summary Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Binds to the core DNA motif of NPPA promoter. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN511024 Nkx2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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