Mouse Nfatc2 activation kit by CRISPRa

SKU GA202871

Nfatc2 CRISPRa kit - CRISPR gene activation of mouse nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Nfatc2
• Locus ID: 18019
• Components:

  GA202871G1, Nfatc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202871G2, Nfatc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202871G3, Nfatc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001037177, NM_001037178, NM_001136073, NM_001291168, NM_001291169, NM_001291170, NM_001291171, NM_001291172, NM_001291173, NM_001291174, NM_001291175, NM_001291176, NM_001291177, NM_001291178, NM_001291179, NM_010899, NR_111897, NR_111898
• UniProt ID: Q60591
• Synonyms: AI607462; NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp
• Summary: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.[UniProtKB/Swiss-Prot Function]