Mouse Nedd9 activation kit by CRISPRa

SKU
GA202858
Nedd9 CRISPRa kit - CRISPR gene activation of mouse neural precursor cell expressed, developmentally down-regulated gene 9
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nedd9
Locus ID 18003
Components

GA202858G1, Nedd9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202858G2, Nedd9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202858G3, Nedd9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001111324, NM_017464
UniProt ID O35177
Synonyms Cas-L; CasL; HEF1; MEF1; Nedd-9; p105
Summary Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN510875 Nedd9 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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