Mouse Myo7b activation kit by CRISPRa

SKU GA202810

Myo7b CRISPRa kit - CRISPR gene activation of mouse myosin VIIB

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Myo7b
• Locus ID: 17922
• Components:

  GA202810G1, Myo7b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202810G2, Myo7b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202810G3, Myo7b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_032394
• UniProt ID: Q99MZ6
• Summary: Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. May link the complex to the actin core bundle of microvilli.[UniProtKB/Swiss-Prot Function]