Mouse Myh9 activation kit by CRISPRa

SKU GA202792

Myh9 CRISPRa kit - CRISPR gene activation of mouse myosin, heavy polypeptide 9, non-muscle

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Myh9
• Locus ID: 17886
• Components:

  GA202792G1, Myh9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202792G2, Myh9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202792G3, Myh9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_022410, NM_181327
• UniProt ID: Q8VDD5
• Synonyms: Fltn; Myhn-1; Myhn1; NMHCIIA; NMMHC-A; NMMHC-IIA; TU72.6
• Summary: During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity). Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.[UniProtKB/Swiss-Prot Function]