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Mouse Ppp1r15a activation kit by CRISPRa

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SKU
GA202781
Ppp1r15a CRISPRa kit - CRISPR gene activation of mouse protein phosphatase 1, regulatory subunit 15A
  $1,657.00
4 Weeks*

Other products for "Ppp1r15a"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ppp1r15a
Locus ID 17872
Components

GA202781G1, Ppp1r15a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202781G2, Ppp1r15a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202781G3, Ppp1r15a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_008654
UniProt ID P17564
Synonyms 9630030H21; Gadd34; Myd116
Summary Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. In case of infection with vesicular stomatitis virus (VSV), impairs viral replication.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN513736 Ppp1r15a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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