Mouse Mybl1 activation kit by CRISPRa

SKU
GA202777
Mybl1 CRISPRa kit - CRISPR gene activation of mouse myeloblastosis oncogene-like 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Mybl1
Locus ID 17864
Components

GA202777G1, Mybl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202777G2, Mybl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202777G3, Mybl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001290397, NM_008651
UniProt ID P51960
Synonyms A-myb; G1-419-6; repro9
Summary Transcription factor that specifically recognizes the sequence 5'-YAACGTG-3' (PubMed:7813437, PubMed:23523368). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism, such as PIWIL1 (PubMed:21750041, PubMed:23523368). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (PubMed:23523368).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN510569 Mybl1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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