Mouse Bloc1s5 activation kit by CRISPRa

SKU
GA202758
Bloc1s5 CRISPRa kit - CRISPR gene activation of mouse biogenesis of lysosomal organelles complex-1, subunit 5, muted
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Bloc1s5
Locus ID 17828
Components

GA202758G1, Bloc1s5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202758G2, Bloc1s5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202758G3, Bloc1s5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_139063
UniProt ID Q8R015
Synonyms 1810074A19Rik; mu; Muted
Summary Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN502184 Bloc1s5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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