Mouse Map2 activation kit by CRISPRa

SKU GA202739

Map2 CRISPRa kit - CRISPR gene activation of mouse microtubule-associated protein 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Map2
• Locus ID: 17756
• Components:

  GA202739G1, Map2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202739G2, Map2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202739G3, Map2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001039934, NM_001310634, NM_008632
• Synonyms: G1-397-34; MAP-2; Mtap-2; Mtap2; repro4
• Summary: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.[UniProtKB/Swiss-Prot Function]