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Mouse Mpz activation kit by CRISPRa

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SKU
GA202709
Mpz CRISPRa kit - CRISPR gene activation of mouse myelin protein zero
  $1,657.00
4 Weeks*

Other products for "Mpz"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Mpz
Locus ID 17528
Components

GA202709G1, Mpz gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202709G2, Mpz gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202709G3, Mpz gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_008623
UniProt ID P27573
Synonyms Mpp; P-zero; P0
Summary This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in the orthologous gene in human are associated with myelinating neuropathies. A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. Alternatively spliced transcript variants have also been found for this gene. provided by RefSeq, Oct 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN510270 Mpz - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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