Mouse Marcksl1 activation kit by CRISPRa

SKU
GA202671
Marcksl1 CRISPRa kit - CRISPR gene activation of mouse MARCKS-like 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Marcksl1
Locus ID 17357
Components

GA202671G1, Marcksl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202671G2, Marcksl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202671G3, Marcksl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_010807
UniProt ID P28667
Synonyms AL022768; AW215397; AW536807; D4Bc1; F52; MacMARCKS; Macs2; Macs3; Mlp; Mrp
Summary Involved in the control of cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation (PubMed:22751924). When unphosphorylated, induces cell migration (PubMed:22751924). When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration (PubMed:22751924). May be involved in coupling the protein kinase C and calmodulin signal transduction systems (Probable).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN509794 Marcksl1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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