Mouse Mip activation kit by CRISPRa

SKU GA202659

Mip CRISPRa kit - CRISPR gene activation of mouse major intrinsic protein of lens fiber

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mip
• Locus ID: 17339
• Components:

  GA202659G1, Mip gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202659G2, Mip gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202659G3, Mip gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_008600
• UniProt ID: P51180
• Synonyms: Aqp0; Cat; Cts; Hfi; Lop; MIP26; MP26; shrivelled; Svl
• Summary: Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.[UniProtKB/Swiss-Prot Function]