Mouse Mef2d activation kit by CRISPRa

SKU GA202631

Mef2d CRISPRa kit - CRISPR gene activation of mouse myocyte enhancer factor 2D

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Mef2d
• Locus ID: 17261
• Components:

  GA202631G1, Mef2d gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202631G2, Mef2d gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202631G3, Mef2d gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001310587, NM_001310593, NM_133665, NM_197994
• Synonyms: C80750
• Summary: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.[UniProtKB/Swiss-Prot Function]