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Mouse Mgrn1 activation kit by CRISPRa

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SKU
GA202617
Mgrn1 CRISPRa kit - CRISPR gene activation of mouse mahogunin, ring finger 1
  $1,657.00
4 Weeks*

Other products for "Mgrn1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Mgrn1
Locus ID 17237
Components

GA202617G1, Mgrn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202617G2, Mgrn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202617G3, Mgrn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001252437, NM_029657, NM_001357061, NM_001357062
UniProt ID Q9D074
Synonyms 2610042J20Rik; md; mKIAA0544; nc
Summary E3 ubiquitin-protein ligase. Mediates TSG101 monoubiquitination at multiple sites. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling. Does not promote MC1R ubiquitination (By similarity). Acts also as a negative regulator of hedgehog signaling (PubMed:29290584).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN510070 Mgrn1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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