Mouse Matk activation kit by CRISPRa

SKU GA202581

Matk CRISPRa kit - CRISPR gene activation of mouse megakaryocyte-associated tyrosine kinase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Matk
• Locus ID: 17179
• Components:

  GA202581G1, Matk gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202581G2, Matk gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202581G3, Matk gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001285853, NM_001285854, NM_001285855, NM_010768
• UniProt ID: P41242
• Synonyms: CHK; HYL; Ntk; p56ntk
• Summary: Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.[UniProtKB/Swiss-Prot Function]