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Mouse Sh2b3 activation kit by CRISPRa

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SKU
GA202480
Sh2b3 CRISPRa kit - CRISPR gene activation of mouse SH2B adaptor protein 3
  $1,657.00
4 Weeks*

Other products for "Sh2b3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Sh2b3
Locus ID 16923
Components

GA202480G1, Sh2b3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202480G2, Sh2b3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202480G3, Sh2b3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_008507
UniProt ID O09039
Synonyms AI429800; Lnk
Summary This gene encodes a member of the SH2B family of adapter proteins that play an important role in T cell receptor signaling. This gene is preferentially expressed in hematopoietic stem cells, hematopoietic progenitors, pre and immature B cells, as well as megakaryocytes and mastocytes. In hematopoietic stem cells, the encoded protein is a key regulator of self-renewal, proliferation and apoptosis. Mice lacking the encoded protein exhibit pre and immature B cell expansion in spleen and the bone marrow. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN515698 Sh2b3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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