Mouse Krt18 activation kit by CRISPRa

SKU GA202372

Krt18 CRISPRa kit - CRISPR gene activation of mouse keratin 18

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Krt18
• Locus ID: 16668
• Components:

  GA202372G1, Krt18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202372G2, Krt18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202372G3, Krt18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_010664
• UniProt ID: P05784
• Synonyms: CK18; K18; Krt1-18
• Summary: When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.[UniProtKB/Swiss-Prot Function]