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Mouse Klc1 activation kit by CRISPRa

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SKU
GA202324
Klc1 CRISPRa kit - CRISPR gene activation of mouse kinesin light chain 1
  $1,657.00
4 Weeks*

Other products for "Klc1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Klc1
Locus ID 16593
Components

GA202324G1, Klc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202324G2, Klc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202324G3, Klc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001025358, NM_001025359, NM_001025360, NM_001025361, NM_001025362, NM_001025363, NM_001081959, NM_008450
Synonyms AI874768; Kns2
Summary Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN508818 Klc1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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