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Mouse Kcnk2 activation kit by CRISPRa

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SKU
GA202276
Kcnk2 CRISPRa kit - CRISPR gene activation of mouse potassium channel, subfamily K, member 2
  $1,657.00
4 Weeks*

Other products for "Kcnk2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Kcnk2
Locus ID 16526
Components

GA202276G1, Kcnk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202276G2, Kcnk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202276G3, Kcnk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001159850, NM_001281847, NM_001281848, NM_010607, NR_027627, NM_001357119
UniProt ID P97438
Synonyms A430027H14Rik; AI848635; TREK-1
Summary Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2 (PubMed:24496152). In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1 (PubMed:24496152).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN508670 Kcnk2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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