Mouse Kcnj16 activation kit by CRISPRa

SKU
GA202267
Kcnj16 CRISPRa kit - CRISPR gene activation of mouse potassium inwardly-rectifying channel, subfamily J, member 16
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Kcnj16
Locus ID 16517
Components

GA202267G1, Kcnj16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202267G2, Kcnj16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202267G3, Kcnj16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001252207, NM_001252208, NM_001252209, NM_001252210, NM_010604
UniProt ID Q9Z307
Synonyms 6430410F18Rik; AI132396; Kir5.1
Summary Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN508655 Kcnj16 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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