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Mouse Kcnj10 activation kit by CRISPRa

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SKU
GA202263
Kcnj10 CRISPRa kit - CRISPR gene activation of mouse potassium inwardly-rectifying channel, subfamily J, member 10
  $1,657.00
4 Weeks*

Other products for "Kcnj10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Kcnj10
Locus ID 16513
Components

GA202263G1, Kcnj10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202263G2, Kcnj10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202263G3, Kcnj10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001039484, NM_020269
UniProt ID Q9JM63
Synonyms BIR10; BIRK-1; Kir1.2; Kir4.1
Summary May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN508649 Kcnj10 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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