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Mouse Itpr1 activation kit by CRISPRa

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SKU
GA202223
Itpr1 CRISPRa kit - CRISPR gene activation of mouse inositol 1,4,5-trisphosphate receptor 1
  $1,657.00
4 Weeks*

Other products for "Itpr1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Itpr1
Locus ID 16438
Components

GA202223G1, Itpr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202223G2, Itpr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202223G3, Itpr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_010585
UniProt ID P11881
Synonyms D6Pas2; ENSMUSG00000072853; Gm10429; InsP3R; insP3R1; Ip3r; IP3R 1; IP3R1; Itpr-1; opt; P400
Summary Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (PubMed:23542070). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN508517 Itpr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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