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Mouse Itga6 activation kit by CRISPRa

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SKU
GA202197
Itga6 CRISPRa kit - CRISPR gene activation of mouse integrin alpha 6
  $1,657.00
4 Weeks*

Other products for "Itga6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Itga6
Locus ID 16403
Components

GA202197G1, Itga6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202197G2, Itga6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202197G3, Itga6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001277970, NM_008397
UniProt ID Q61739
Synonyms 5033401O05Rik; AI115430; Cd49f; VLA-6
Summary This gene encodes a protein that is a member of the integrin superfamily. Integrins are transmembrane receptors involved cell adhesion and signaling, and they are subdivided based on the heterodimer formation of alpha and beta chains. This protein has been shown to heterodimerize with beta 4 to bind laminin and to form the main component of hemidesmosomes, which mediate attachment of epithelia to basement membranes. In mouse, deficiency of this gene is associated with absence of hemidesmosomes, severe skin blistering, and early post-natal death. In humans mutations of this gene are associated with epidermolysis bullosa. Alternative splicing results in multiple transcript variants that encode different protein isoforms. provided by RefSeq, May 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN508478 Itga6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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