Mouse Il13ra2 activation kit by CRISPRa

SKU
GA202124
Il13ra2 CRISPRa kit - CRISPR gene activation of mouse interleukin 13 receptor, alpha 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Il13ra2
Locus ID 16165
Components

GA202124G1, Il13ra2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202124G2, Il13ra2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202124G3, Il13ra2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_008356
UniProt ID O88786
Synonyms CD213a2; IL-13R-alpha-2
Summary This gene encodes a receptor protein that binds to interleukin 13 (IL-13) with very high affinity. The encoded protein acts as a decoy receptor, and does not elicit any signal upon the binding of IL-13. Mice lacking the encoded protein exhibit increased levels of serum immunoglobulins, immune-dependent production of interferon gamma and, increased bone marrow macrophage progenitor frequency. Macrophages lacking the encoded protein release less nitric oxide and IL-12 in response to lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
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Other Versions
SKU Description Size Price
KN508230 Il13ra2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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