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Mouse Ndst1 activation kit by CRISPRa

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SKU
GA202023
Ndst1 CRISPRa kit - CRISPR gene activation of mouse N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

TA355028 Rabbit Polyclonal Anti-NDST1 Antibody
100 ug
$640.00

Other products for "Ndst1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ndst1
Locus ID 15531
Components

GA202023G1, Ndst1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202023G2, Ndst1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202023G3, Ndst1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_008306, NM_001348100, NM_001348101, NM_001348102, NM_001348103, NM_001348146
UniProt ID Q3UHN9
Synonyms 1200015G06Rik; b2b2230Clo; Hsst; NDST-1
Summary Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN510816 Ndst1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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